Identity
Calcium alpha-ketoglutarate
The calcium salt of alpha-ketoglutarate is distinct from an unspecified AKG blend.
Premium Quality
Ca-AKG 500mg | Calcium Alpha-Ketoglutarate
500mg calcium alpha-ketoglutarate per capsule. Human longevity outcomes have not been established.
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- Key Benefits
- Calcium Alpha-Ketoglutarate: 500mg declared
- 1 capsule per serving
- Evidence level stated for each active ingredient
- Complete label ingredient breakdown below
Ingredients
- Calcium Alpha-Ketoglutarate (500mg); Rice flour; Cellulose capsule
Suggested Use
- Label reference: 1 capsule per serving. Follow the physical product label for directions and consult a qualified healthcare professional when appropriate.
- Lab Tested
- U.S. Based
- GMP Certified
Inside the formula
A Krebs-cycle metabolite with promising—but preclinical—longevity research.
Alpha-ketoglutarate has a well-established role in metabolism. That biology and the animal longevity literature are interesting; neither proves a human longevity benefit from this capsule.
1 capsule per serving500mg calcium alpha-ketoglutarate
Biology
Metabolic intermediate
Alpha-ketoglutarate participates in the citric-acid cycle and amino-acid metabolism.
Evidence
Longevity data are preclinical
The widely cited lifespan result comes from mice, not a completed human longevity trial.
01
500mg
Preclinical evidence · mouse study
The metabolic intermediate
Calcium Alpha-Ketoglutarate
Ca-AKG · calcium salt of alpha-ketoglutarate
What it is: Alpha-ketoglutarate is an endogenous metabolic intermediate; Ca-AKG is a calcium salt used to deliver it orally.
Evidence context: A prominent 2020 study reported healthspan and lifespan findings in mice. Completed human trials have not established that Ca-AKG extends lifespan.
How it fits the formula
Read the preclinical mouse studyThe single-active format keeps the compound clear while the page labels longevity research by its actual evidence tier.
Every other label-listed ingredient
What the supporting ingredients actually do.
Rice flour
A label-listed inactive carrier used for consistent capsule fill.
Cellulose capsule
The plant-derived capsule shell.
The formulation rationale
Established metabolism. Unestablished longevity outcome.
Endogenous metabolite + oral salt: AKG occurs in human metabolism; Ca-AKG is the calcium salt used in this capsule.
Basic biology + animal research: A metabolic role can motivate preclinical studies, but does not predict a human lifespan effect by itself.
Animal signal + human uncertainty: The mouse study is clearly identified as preclinical so shoppers can weigh it appropriately.
60 capsules60 label servings
Choose your quantityIngredient-profile photography: Unsplash. Image is illustrative and does not establish batch provenance.
- What It Does
Each capsule supplies 500mg of calcium alpha-ketoglutarate (Ca-AKG), the calcium salt of a metabolic intermediate.
- How It Works
Alpha-ketoglutarate participates in the citric-acid cycle and amino-acid metabolism. Longevity claims are based largely on preclinical work, and human lifespan extension has not been demonstrated.
- Science-Backed Research
Evidence tier is identified for each active ingredient
Human, preclinical and formulation evidence are kept separate
Primary-source research is linked in the ingredient breakdown
The exact finished formula is not presented as clinically tested
- Ideal For
Shoppers comparing clearly declared active amounts
People who value full inactive-ingredient disclosure
Adults who follow the physical label and review contraindications
- Clinical Research
Preclinical Ca-AKG healthspan study
A 2020 mouse study reported lifespan and frailty findings. This was not a human clinical trial and cannot establish that Ca-AKG extends human life.
A 2020 mouse study reported lifespan and frailty findings. This was not a human clinical trial and cannot establish that Ca-AKG extends human life.
Frequently Asked Questions
Everything you need to know about our premium supplements
Each capsule supplies 500mg of calcium alpha-ketoglutarate (Ca-AKG), the calcium salt of a metabolic intermediate.
Alpha-ketoglutarate participates in the citric-acid cycle and amino-acid metabolism. Longevity claims are based largely on preclinical work, and human lifespan extension has not been demonstrated.
No finished-product clinical trial is cited. The research links provide ingredient-level context and are labeled by evidence type. Human longevity benefit has not been established. The linked research was conducted in mice; extrapolating its lifespan or frailty findings directly to people would be inappropriate.
Label reference: 1 capsule per serving. Follow the physical product label for directions and consult a qualified healthcare professional when appropriate.
