Build the foundation
NAD+ precursor
500mg NMN supplies material used in NAD+ biosynthesis.
-19%
Premium Quality
NMN Advanced Longevity Complex 1200mg Total Actives | NAD+ Support
One daily longevity formula, six complementary actives. Each 2-capsule serving provides 500mg NMN with TMG, pterostilbene, trans-resveratrol, quercetin phytosome and apigenin—1,200mg total actives in 60 vegan capsules.
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- Key Benefits
- 1,200mg total active ingredients per 2-capsule serving
- 500mg NMN to support NAD+ metabolism
- TMG plus four complementary polyphenols and flavonoids
- 60 vegan capsules for 30 daily servings
Ingredients
- β-Nicotinamide Mononucleotide (NMN) 500mg, TMG (Betaine Anhydrous) 250mg, Pterostilbene 200mg, Trans-Resveratrol 100mg, Quercetin Phytosome (Sophora japonica flower) 100mg, Apigenin 50mg. Other ingredients: Rice Flour, Vegetable Cellulose Capsule.
Suggested Use
- Adults take 2 capsules daily, or as directed by a healthcare professional.
- Lab Tested
- U.S. Based
- GMP Certified
Formula architecture
Six ingredients. Three complementary jobs.
This is not six versions of the same idea. NMN supplies an NAD+ precursor, TMG supports normal methyl-group metabolism, and four structurally different polyphenols and flavonoids broaden the formula’s nutritional coverage.
One 2-capsule serving1,200mg total active ingredients
Support the cycle
Methylation support
250mg TMG contributes methyl groups through the BHMT pathway.
Broaden the network
Four plant compounds
Two stilbenes, one flavonol and one flavone add complementary chemistry.
01
500mg per serving
The NAD+ precursor
NMN
β-Nicotinamide Mononucleotide
What it is: NMN is a nucleotide the body can use when making NAD+, a coenzyme involved in cellular energy transfer and many enzyme reactions.
Evidence context: Randomized human trials of NMN alone have reported increases in blood NAD+ after daily supplementation.
How it fits the formula
Read the NMN human trialIt establishes the precursor foundation; the other actives are included to complement adjacent methylation and polyphenol pathways.
02
250mg per serving
The methyl donor
TMG
Betaine Anhydrous
What it is: TMG, also called betaine, can donate a methyl group through the BHMT pathway, which remethylates homocysteine to methionine in the liver and kidneys.
Evidence context: Human studies and meta-analyses have examined betaine in normal homocysteine metabolism; response depends on dose, diet and individual context.
How it fits the formula
Review the betaine evidenceIt gives the formula dedicated methyl-group support alongside the NAD+ precursor rather than adding another overlapping polyphenol.
03
200mg per serving
The complementary stilbene
Pterostilbene
Dimethylated Stilbene
What it is: Pterostilbene is a methylated relative of resveratrol that occurs naturally in blueberries. Its structure is more lipophilic than resveratrol.
Evidence context: Human studies have evaluated pterostilbene at 200mg per day, including short-term safety research; metabolic outcomes vary by study and population.
How it fits the formula
See the human safety studyIt adds a structurally distinct stilbene, broadening the blend beyond resveratrol alone without implying that the two are interchangeable.
04
100mg per serving
The extensively studied stilbene
Trans-Resveratrol
Purified Trans Isomer
What it is: Trans-resveratrol is the trans form of a polyphenol found in grape skins and several berries. It is absorbed, then rapidly metabolized in humans.
Evidence context: A large clinical literature exists, but reviews still find important differences between formulations, doses and outcomes—there is no consensus therapeutic use.
How it fits the formula
Explore the clinical reviewPaired with pterostilbene, it supplies a second stilbene profile while the formula remains transparent about the limits of finished-blend evidence.
05
100mg per serving
The enhanced-delivery flavonol
Quercetin Phytosome
Sophora japonica Flower
What it is: Quercetin is a plant flavonol. A phytosome associates it with food-grade phospholipids to improve dispersion and oral uptake.
Evidence context: A randomized human crossover pharmacokinetic study reported higher quercetin absorption from a phytosome formulation than from standard quercetin.
How it fits the formula
Read the absorption studyIt expands the polyphenol network into the flavonol family and uses a delivery format selected to address quercetin’s naturally limited absorption.
06
50mg per serving
The finishing flavone
Apigenin
Plant Flavone
What it is: Apigenin is a flavone found naturally in foods and botanicals including parsley, celery and chamomile.
Evidence context: Preclinical work has explored apigenin in relation to the NAD+-consuming enzyme CD38. Human outcome evidence remains limited, so this is mechanism context—not a promised result.
How it fits the formula
View the preclinical mechanism studyIt completes the blend with a distinct flavone, complementing quercetin’s flavonol structure and the two stilbenes.
The synergy rationale
Designed to complement—not simply overlap.
Precursor + pathway support: NMN and TMG perform different nutritional jobs, pairing NAD+ precursor support with normal methyl-group metabolism.
Multiple polyphenol families: pterostilbene and trans-resveratrol are stilbenes; quercetin is a flavonol; apigenin is a flavone. Their structures and research profiles are related, but not identical.
Delivery considered: quercetin is included as a phytosome to address absorption, while pterostilbene’s methylated structure differs from resveratrol’s.
60 vegan capsules30 daily servings
Choose your quantityBotanical images provide ingredient context and do not claim manufacturing provenance. Quercetin image: “Sophora japonica (1b)” by Picasa, CC BY-SA 3.0, cropped and optimized. Other reference photography is sourced from Unsplash.
- What It Does
A six-active formula organized around three complementary jobs: NMN supplies an NAD+ precursor, TMG supports normal methyl-group metabolism, and pterostilbene, trans-resveratrol, quercetin phytosome and apigenin add structurally distinct polyphenol and flavonoid support. Each serving provides 1,200mg total actives, including 500mg NMN.
- How It Works
The formula is designed as a layered system rather than six overlapping ingredients. NMN provides precursor support for NAD+ biosynthesis; TMG contributes methyl groups through the BHMT pathway; two stilbenes, one flavonol and one flavone broaden the plant-compound profile. Quercetin is delivered as a phytosome to address absorption. The exact finished formula and the proposed six-way synergy have not been clinically tested.
- Science-Backed Research
Randomized human trials of NMN alone have reported increases in blood NAD+ after supplementation.
TMG functions as a methyl donor in the BHMT pathway involved in normal homocysteine metabolism.
Pterostilbene and trans-resveratrol are related but structurally distinct stilbenes with different pharmacokinetic profiles.
Quercetin phytosome has human absorption data; apigenin’s NAD+-related mechanism evidence is primarily preclinical.
- Ideal For
Adults seeking a simplified daily longevity supplement routine
People who want NMN paired with complementary TMG and polyphenols
Health-conscious adults focused on NAD+ and cellular-energy support
Vegan supplement users looking for a 30-day supply
- Clinical Research
Randomized human research on NMN
A 60-day, randomized, multicenter, double-blind, placebo-controlled trial in 80 healthy middle-aged adults reported increased blood NAD concentrations after daily NMN at 300mg, 600mg or 900mg. NMN was well tolerated in that study. This research evaluated NMN—not this finished six-ingredient formula.
A 60-day, randomized, multicenter, double-blind, placebo-controlled trial in 80 healthy middle-aged adults reported increased blood NAD concentrations after daily NMN at 300mg, 600mg or 900mg. NMN was well tolerated in that study. This research evaluated NMN—not this finished six-ingredient formula.
Frequently Asked Questions
Everything you need to know about our premium supplements
No. The 1,200mg figure is the combined amount of all six active ingredients per 2-capsule serving. Each serving contains 500mg of NMN.
Adults take 2 capsules daily, or follow the directions provided by their healthcare professional. One bottle contains 30 daily servings.
This formula already contains NMN, TMG, pterostilbene, trans-resveratrol, quercetin phytosome and apigenin. Review your full supplement and medication routine with a healthcare professional before adding overlapping products.
Yes. The label lists a vegetable cellulose capsule. The other ingredient is rice flour.
Responses to supplements vary, and no specific result or timeline can be promised. Consistent use as directed and an appropriate healthy lifestyle are important.
The formula is organized in layers: NMN supplies an NAD+ precursor, TMG supports normal methyl-group metabolism, and four structurally different polyphenols and flavonoids broaden the nutritional profile. This describes the formulation rationale; the exact finished blend and its six-way synergy have not been clinically tested.
